Nabble - Bio.net - Biochrom

Bioprotocols online

2009-12-10T18:40:16Z

Sciclips has launched a unique database of bioprotocols for
researchers. Researchers will have free access to these bioprotocols
which have been extracted from published journal articles and patents/
patent applications. We are the first to list protocols from published
US patents, US patent and WO (PCT) applications. We have thousands of
protocols on molecular biology, proteomics, biological imaging,
virology, immunology, stem cells, drug discovery, immunoassays, cell
biology, epigenetics, genomics, plant biology, microbiology, tissue
microarrays and more. In addition to this, we have also listed new
sections on high throughput screening (HTS) and biopharmaceutical
assay protocols. All the protocols are linked to the articles or
patent/patent application . Please follow this link to see the
complete list of our bioprotocols online: http://www.sciclips.com/sciclips/bio-protocols.do

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For Jim Barron re: Differences between H63D and C282Y HFE mutations

2009-09-20T12:27:12Z

Hi Jim

I am following your post made 27 Feb 1999 so I hope you are still t this address, if you are I would like to talk to you about your hypothesis about the difference between the HFE genes and perhaps earlier damage in people with H63D. Has this since been proved or disproved? Looked into further?

Kind regards

Susie

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Forthcoming papers in Chromosome Research

2009-01-31T02:11:04Z

Dear Chromosomers,

Forthcoming papers in the journal Chromosome Research is updated.
Please visit
http://www.chromosome.net/cr-forthcoming.html#recent
(The most recent entries @ 31st January 2009)

Sincerely,

Shigeki Nakayama @ chromosome.net

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Fw: International Conference "Chromosoma 2009" in Novosibirsk, Russia

2009-01-28T01:04:23Z

Dear Chromosomers,

Forward information of International Conference "Chromosome
2009" (August 31- September 6, 2009) in Russia.

Sincerely,

Shigeki Nakayama @ chromosome.net

>Dear colleagues,
>
>We are pleased to announce that the International Conference
"Chromosome 2009" will be held on August 31- September 6, 2009 at the
House of Scientists, Akademgorodok, Novosibirsk, Russia.
>
>The topics of the conference will be Heterochromatin Regions of
Chromosomes and Chromatin Structure; Mapping of Chromosomes, their
Evolution and Comparative Analysis; Mechanisms of Dosage Compensation
and of Cell Division; Chromosomes Organization in The Nucleus, and
Particularized Chromosome Structures. The goal of the Conference is
to bring together geneticists and cytologists to share the latest
scientific and clinical results and to develop a spirit of close
cooperation.
>
>Looking forward to meeting you at "Chromosome 2009" (http://
www.bionet.nsc.ru/meeting/chromosome2009/en/main.html) .
>
>Chairman of the Organizing Committee,
>Full Member of the Russian Academy of Sciences
>Igor ZHIMULEV
>
>

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web page of ICC2009

2008-12-09T16:47:49Z

Dear Chromosomers,

The update of the 17th International Chromosome Conference in Boone,
N.C. June 23-26, 2009 was announced.
The new address is http://www.biology.colostate.edu/icc2009.

In http://rydberg.biology.colostate.edu/icc2009/ImpDatesC.html
> 23rd March 2009 is Abstract Submission Deadline.
> 23rd April 2009 is Deadline for early registration.

Sincerely,

Shigeki Nakayama @ chromosome.net

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Forthcoming papers in Chromosome Research

2008-12-02T04:36:10Z

Dear Chromosomers,

Forthcoming papers in the journal Chromosome Research is updated.
Please visit
http://www.chromosome.net/cr-forthcoming.html

Sincerely,

Shigeki Nakayama @ chromosome.net

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Forthcoming papers in Chromosome Research

2008-08-23T04:21:12Z

Chromosome Research 2008 Scholarly Manuscript Prize

2008-05-26T04:05:55Z

Dear Chromosomers,

Chromosome Research 2008 Scholarly Manuscript Prize is announced.
http://www.chromosome.net/ScholarlyManuscriptPrize2008.html

Sincerely,

Shigeki Nakayama @ chromosome.net

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Forthcoming papers in Chromosome Research

2008-05-23T06:02:02Z

Dear Chromosomers,

Forthcoming papers in the journal Chromosome Research is updated.
http://www.chromosome.net/cr-forthcoming.html

Sincerely,

Shigeki Nakayama @ chromosome.net

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FW: Florennce / Italy Immunology Conference/DEADLINE REMINDER: MARCH 30TH, 2008

2008-03-17T11:26:27Z

DEADLINE REMINDER for submission of abstract and poster: MARCH 30TH,
2008

FRONTIERS IN IMMUNOLOGY RESEARCH
2008 INTERNATIONAL CONFERENCE
www.firnweb.com

FLORENCE, ITALY
July 22-26, 2008
Hotel Croce di Malta

The Frontiers in Immunology Research Network (FIRN) invites you to
participate in its 2008 Conference to be held in the Florence, Italy, at
the
Croce di Malta Hotel, July 22-26. The conference welcomes researchers
from
academia, corporations, governments and other organizations.
Participants may present their research findings, display their posters,
participate in roundtables or simply observe. To participate as a
PRESENTER please submit via email and post ABSTRACTS and/or brief
descriptions of POSTERS (of no more than 200 words) along with your
complete details by March 30th, 2008 as follows:

Frontiers in Immunology Research Network (FIRN)
64 Holden Street
Worcester MA 01605-3109
USA
Tel.: 508-852-3937, Fax: 508-595-0089
Email: hkan@...
Web: http://www.firnweb.com

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Event: Unlock Insight from Your Clinical Data

2007-09-13T18:18:47Z

http://www.inforsense.com/index.php?id=204

Event: Unlock Insight from Your Clinical Data
Presenters Info: Hai Hu, Senior Director of Biomedical Informatics,
Windber Research Institute

Michael N. Liebman, Ph.D., Executive Director, Windber Research
Institute & President and Managing Director, Strategic Medicine, Inc

Mick Correll, Director Clinical Solutions, InforSense

Host: Dave Menninger, VP Marketing & Product Management, InforSense
Date: 19 September 2007
Time: 11:00 ET (New York)
Duration: 1 hour including Q&A

Description:
>From academic medical research centers to hospitals and health
insurers, the healthcare industry continues to improve its
capabilities for electronic data capture. Despite these advances, a
gap remains in the ability of these IT systems to deliver knowledge
and insight back to the very researchers and clinicians they are built
to support.

Please join Dr. Hai Hu from the Windber Research Institute to learn
about some of the tools and techniques he and his colleagues are using
to bridge this gap and deliver insight to their clinical community.

In this webcast you will learn how to:

Move beyond primary data capture systems to an analytical environment
Explore patient populations: trend identification, hypothesis
generation, and cohort analysis
Make the most of longitudinal patient records and investigate temporal
relationships of life and medical events
Integrate patient and sample information to enhance tissue
repositories
Who should attend:

Clinical and biomedical researchers
Data analysts and informaticians
Medical and scientific officers
Healthcare IT managers

About InforSense
InforSense Ltd., the leader in embedded enterprise analytics, enables
organizations to orchestrate and optimize their business-critical
decision-making processes. Leading pharmaceutical and biotechnology,
consumer goods, healthcare, financial services manufacturing and
communications companies are using the company's flagship product,
InforSense, to enhance productivity by embedding analytics within
their business processes. The company is privately held, with
European headquarters in London, UK and North American headquarters in
Cambridge, Massachusetts.

About Windber Research Institute
The Windber Research Institute is a translational medicine research
center that focuses on bringing the problems in the clinic back to the
research laboratory for analysis at the genomic, proteomic, image and
informatic levels. It is focused in its research areas on women's
health, including obstetrics and gynecologic diseases including
breast, ovarian, endometrial and cervical cancers, cardiovascular
disease, obesity and diabetes, and processes of normal aging including
menopause. It has worked closely with its partners at InforSense to
develop an integrated research environment that is being extended to
support physician decision making in collaboration with the patient.
Major efforts in tissue banking, patient data acquisition and genomic
research (sequencing, genotyping, gene expression, whole genome
analysis) and proteomics (protein separation and identification)
comprise the experimental focus. The biomedical informatics efforts
include data modelling and warehousing, data mining and research into
the development of disease models for risk assessment, prevention and
early detection, including environmental and lifestyle factors.

Windber Research Institute collaborates closely with the Walter Reed
Army Medical Center and with the Joyce Murtha Breast Care Center, the
University of Pittsburgh Medical Center and Cancer Institute,
Georgetown University, and the University of California-San Francisco
in the areas of women's health, cardiovascular disease and obesity. It
is a private, non-profit research institute that is located
approximately 1.5 hours from Pittsburgh, Pennsylvania, in the Laurel
Highlands Mountains.
Additional information can be obtained at www.wriwindber.org.

About Strategic Medicine, Inc
Strategic Medicine, Inc (SMI) is an emerging healthcare company
focused on translational medicine that will capitalize on the broad
trend in healthcare information technology to integrate patient
medical information to facilitate better clinical decisions, assess
and improve quality of care, share information among hospital
communities to improve outcomes, and provide rich clinical information
to pharmaceutical companies for drug development and clinical
candidate selection. SMI defines translational medicine as working
with clinicians to identify real diagnostic and therapeutic problems,
moving them into the research environment, and providing solutions
through data analysis that are immediately applicable to improving the
quality of care in the clinic. By merging clinical, molecular and
imaging data, in a patient-centric data model that is longitudinally
focused, while accessing a unique tissue repository, SMI is developing
one of the first systems that can lead to viable translational and
preventive medicine as a true clinical opportunity.

SMI is uniquely positioned in this evolving market. In association
with the Windber Research Institute and its partners, the Company has
developed a flexible and scaleable Internet-based data system that
enables hospitals and hospital networks to realize near term data
security, productivity and quality of care improvements, while paving
the way for clinical trial participation, and the long term benefits
of a truly interoperable, patient centric, personalized health
record.
Additional information can be obtained at www.strategicmedicine.com

For questions on the webcast please e-mail information@...

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Colet Court,
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London, W6 7JP
United Kingdom InforSense - North America
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USA

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©2007 InforSense Ltd. All rights reserved. InforSense, the InforSense
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How New Insights from Literature Mining Can Enhance Analysis in Genome Wide Association Studies

2007-07-06T09:24:35Z

http://www.inforsense.com/index.php?id=181

Event:
How New Insights from Literature Mining Can Enhance Analysis in
Genome Wide Association Studies

Presenter Info:
Jonathan Ratcliffe, Application Development Manager, InforSense
David Milward, CTO, Linguamatics

Host:
Robin Munro, Director BioMedical Solutions, InforSense

Date:
17 July 2007

Time:
15:00 BST (London), 12:00 ET (New York)
18:00 BST (London), 15:00 ET (New York)

Duration:
1 hour including Q&A

Description:
Do you have the right tools for performing Genome Wide Association
Studies? Can you process a million SNPs across thousands of samples?
Are you still conducting your literature searches using Google? Do you
waste too much time reading irrelevant internal and external
documents? Attend this complimentary webcast and learn how to combine
literature mining and statistical genetics in a single, integrated
environment.

See and hear how:

InforSense GenSense can be used for genome wide association studies.
New knowledge from publications can be easily included in your
analyses using Linguamatics I2E.
Natural language processing can be used to provide the right
biomedical context for your searches.
Information mined from publications can be processed, visualized and
deployed by business users.
See these concepts demonstrated in an application that examines
genetic variability associated with Parkinson's disease and then
interprets these results by mining publications for information which
may help explain the nature of the relationship between the genetic
variation and the disease.

Who should attend:

Bioinformaticians
Librarians / Information Services
Text Mining Professionals in Pharma, Biotech & Academia

About InforSense
InforSense Ltd., the leading provider of embedded enterprise
analytics, enables organizations to orchestrate and optimize their
business-critical decision-making processes. Leading pharmaceutical
and biotechnology, consumer goods, healthcare, financial services,
manufacturing and communications companies are using the company's
flagship product, InforSense, to enhance productivity by embedding
analytics within their business processes. The company is privately
held, with European headquarters in London, UK and North American
headquarters in Cambridge, Massachusetts.

About Linguamatics
Linguamatics helps organizations to maximize the value derived from
information resources, through effective deployment of innovative
natural language processing (NLP) based technology. The versatile
interactive information extraction system, I2E, helps organizations to
do much more than simply cope with vast quantities of information. Its
unique combination of search and text mining helps organizations to
turn this information into a competitive advantage. From life sciences
and healthcare to business intelligence; from media analysis to
security, users mine large collections of documents, extracting
relevant facts and relationships from content such as scientific
papers, news feeds, patents, or business reports. Linguamatics was
founded in 2001, and is based in Cambridge, UK.

For questions on the webcast please e-mail information@...

--------------------------------------------------------------------------------

InforSense Ltd
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100 Hammersmith Road,
London, W6 7JP
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InforSense - North America
155 Second Street,
Cambridge, MA 02141
USA

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codon usage bias in humans ?

2007-06-05T15:55:55Z

Hi,

I have been studying biology in the 70s and been out of the loop for a
while.
I came across this on the web and try to figure if it makes any
scientific sense - I know all possible codons are assigned to amino
acids (or stop/start) but is there a bias in humans as to not use any
of them or many as proposed here:

does the following text make any sense?

-------------------

He was taken to UCLA to see what was going on and those tests showed
that he didn't have normal human DNA. In the human DNA we have 4
nucleic acids that combine in sets of 3 producing 64 different
patterns that are called codons. Human DNA all over the world always
has 20 of these codons turned on and the rest of them are turned off,
except for 3 which are the stop and start codes, much like a computer.
Science always assumed that the ones that were turned off were old
programs from our past. I've always seen them like application
programs in a computer. Anyway...this boy had 24 codons turned on - 4
more than any other human being. Then they tested this kid to see how
strong his immune system was.

----------------------

thanx

-sam

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Whole Genome Association Study of Schizophrenia

2007-05-04T11:48:17Z

WHOLE GENOME ASSOCIATION OF SCHIZOPHRENIA

A Golden Helix Webinar

Presenter: Todd Lencz, Ph.D., Feinstein Institute for Medical Research
Date: Wednesday, May 9th
Time: 1:00pm ET
Abstract: Dr. Lencz will discuss the various data management and
analysis steps conducted in his recently published WGA study of
schizophrenia.

Register Now!: <https://www.gotomeeting.com/register/625338501>

----------------

Schizophrenia is a complex disease marked by high heritability
(70-80%), yet few disease genes have been clearly identified and
linkage studies have failed to converge.

Whole genome association (WGA) is a promising, hypothesis-free
approach to discovering novel genetic susceptibility loci for diseases
such as schizophrenia. However, WGA entails numerous methodological
challenges, including:

- Management and manipulation of very large datasets

- Multiple quality control procedures

- Statistical analysis correcting for multiple comparisons.

Join Todd Lencz, Ph.D., Senior Psychologist at The Feinstein Institute
for Medical Research (FIMR), to learn how he and his team used Golden
Helix' HelixTree software to overcome these difficult challenges on
their quest to discover a novel gene that appears to increase the risk
of developing schizophrenia.

In a sample of 178 patients with schizophrenia and 144 controls, Dr.
Lencz and his team of psychiatric researchers from FIMR utilized
HelixTree software to analyze WGA data derived from Affymetrix 500K
microarrays. They identified a novel susceptibility locus in the
pseudoautosomal region of the X/Y chromosomes. The results were
published last month in the high-impact journal, Molecular
Psychiatry.

In this webinar Dr. Lencz will walk through the data management and
analytic steps conducted in HelixTree that helped make this discovery
possible.

Don't miss this opportunity to learn how you can apply these same
technologies to accelerate your research!

Register Now! <https://www.gotomeeting.com/register/625338501>
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SNP Chip Data Analysis for Whole Genome Association Studies

2007-04-19T11:16:25Z

http://www.inforsense.com/webcast.html?id=11

--------------------------------------------------------------------------------

Event:
SNP Chip Data Analysis for Whole Genome Association Studies:
Rapid identification of phenotype/genotype associations and predictive
biomarkers using GenSense

Date and time:
24 April 2007
3:00pm UK / 10:00am EST / 7:00am PST
6:00pm UK / 1:00pm EST / 10:00am PST

Presenter(s) Info:
Robin Munro, Director of Biology Solutions, InforSense
Patton Fast, Director of Strategic Partner Programs, InforSense

Duration:
45 minutes

Description: SNP Chip Data Analysis for Whole Genome Association
Studies

With the throughput that is possible from the new genotyping
platforms, the promise of delivering novel biomarkers is now within
reach. Whole genome association studies are becoming commonplace but
it is clear that current analysis tools do not maximize the potential
value of the underlying high cost experiments. Analytic software needs
to be highly flexible to enable ad hoc integration of many different
types of data and algorithms and to compare outputs from different
approaches.

In this webcast you will learn how InforSense GenSense can help you
analyze high volume SNP chip data and accelerate the identification of
phenotype/genotype associations and new predictive biomarkers. You
will see how to use data from new generation SNP chips, combined with
current genome data sources and the latest statistical genetics
techniques, to quickly identify predictive and diagnostic biomarkers.
We will also show how GenSense is used for building ad hoc analyses as
well as integrating custom analysis methods and workflows for gene
annotation and text mining.

In this free webcast, you will learn how to:

Manage and analyze large volume genotyping data.
Assess chip quality through a range of QC procedures.
Interpret results and find new phenotype/genotype and case control
associations.
Link SNPs to genes, pathways and processes for interpretation in the
relevant biological context.
Access these functionalities via a simple and intuitive portal.

InforSense GenSense enables the analysis of data from the latest
generation of genotyping platforms. It has been specifically designed
to assist researchers understand complex analyses, quickly find
interesting SNP's and produce reports with easy to understand
graphical summaries and interactive visualizations of large data sets.
The first version of GenSense supports data from both Illumina and
Affymetrix and supports links to standard genomics data sources such
as Entrez Gene, HapMap and dbSNPs.

InforSense Ltd., the leader in integrative analytics, enables
organizations to orchestrate and optimize their business-critical
decision-making processes. Leading pharmaceutical and biotechnology,
consumer goods, financial services companies, and research institutes
are using the company's flagship product, InforSense KDE, to enhance
productivity across life science R&D, healthcare, and business
analytics. The company is privately held, with European headquarters
in London, UK and North American headquarters in Cambridge,
Massachusetts.

For questions on the webcast please contact Perry Aiello at +1 760 587
1077 or information@...

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[Molecular-evolution] Human Chromosome Two: Evidence of First-degree Consanguity in Human Evolution

2007-01-01T07:22:45Z

Dear Dr. Rowell,

I read your interesting reply to Jamie Love's question about chromosome 2 fusion in humans and the necessity, or lack of it, for inbreeding to achieve successful mating. If there is no reproductive barrier or reduction in fertility in many cases, then should it not be rather common for a species to have variation in numbers of chromosomes, just as there is variation in other heritable characteristics that are not strongly selected against? But this does not seem to be the case.

Ron

Ron Larson

Chair, and GG Brown Professor of Chemical Engineering

Professor of Macromolecular Science and Engineering, Biomedical Engineering, and Mechanical Engineering

Dept. of Chem. Engng.

2300 Hayward

Univ. of Michigan

Ann Arbor, MI 48109-2136

rlarson@...

734 936-0772

FAX 734 763-0459

http://www.engin.umich.edu/dept/cheme/people/larson.html

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CONCENTRATION OF CONCAVALIN A FOR DOG KARYOTYPING

2006-12-31T21:36:23Z

Juliette,

I was hoping if you could send me details regarding the concentration of concavalin A or any other mitogen used for canine karyotyping.

thanking you

abraham j.p.

department of animal breeding and genetics

college of veterinary and animal sciences, mannuthy, kerala

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Human Chromosome Two: Evidence of First-degree Consanguity in Human Evolution

2006-11-12T11:22:58Z

The Robertsonsian fusion that formed human chromosome number two (from
ancestral 2A and 2B, as it is preserved in the other apes) should have
caused a serious reproductive barrier, overcome only by consanguity of
the highest order; mating amongst first-degree relatives. Any breeding
outside the immediate family would have lead to unacceptable
chromosomal imbalances.
No aneuploidy of human #2 (p or q or all) has ever survived.
I cannot imagine a scenario in which this fusion (2a and 2b) could have
survived, and become fixed in our species, unless immediately followed
by consanguity in our lineage.

I often mention this paradox to my Genetics students and I have
searched the literature but I have never found a better explanation nor
a statement in a textbook that all of us (humans) are descendants from
an incestuous family. Yet it is apparent from the facts (explained
above) that we are.

The explanation that the "complete" chromosome two is ancestral and
that the lineages of the other apes (gorilla, chimpanzee, orangutan)
have each and independently experienced centromeric breaks, is not
parsimonious and not accepted by experts in evolution. (It might
comfort those wishing to blame incest on the non-human apes but it is
not very scientific.)

If this fusion occurred recently there should be an excessive amount of
homozygosity (autozygosity) of genes on human chromosome two as
compared with the genes on other chromosomes (assuming that, after the
consanguity, the descendants eventually outbreed and the "new"
number two chromosome somehow became fixed in our descendants). I do
not know if anyone has surveyed the SNPs and alleles for these
chromosomal comparisons but such data might allow a molecular clock
method to determine if the event occurred recently (Homo sps) or
farther back in time (Australopithecus sps).

I am not suggesting that this fusion is what makes us human. Indeed, I
doubt that it is. However, maintaining a balanced chromosomal
complement would have provided a strong reproductive barrier. Mating
with someone with the "old" 2A and 2B karyotype would have resulted
in reduced fecundity due to lethal aneuploidy and errors in meiotic
disjunction. We often speak of humanity as having evolved through a
bottle neck of a few dozen individuals. Perhaps, at least with regards
to our number two chromosome, that bottle neck was one male and one
female from the same family. Placed in the context of fairy tales, I
conclude that Adam and Eve were brother and sister or parent and
offspring.

I look forward to your discussion.

Sincerely,

Dr Jamie Love

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[Bioforum] Re: Blond Child, Brownhaired Adult

2006-09-05T07:05:42Z

> Cold Spring, no less) once explained this to me, but I pretty much
> forgot. I
> think he said something that there are competing traits and the dark one
> wins
> out in adulthood. Someone also suggested that the darker pigment is
> produced
> more under certain circumstances. The above also applied to me, and I
> became
> dark haired about the time I started school. (I do have adult blond
> cousins

> I have also heard something that when people are highly inbred,
> the
> dominant gene becomes more pronounced, but if they just vary a bit
> (like
> marry from a hundred miles away instead of the next village) the
> recessive
> traits do reappear? Also that when folks tend to be undernourished,
> the
> dominant phenotypes rule more strongly? My blond ancestors were all
> born
> before 1900 and my blond cousins after 1969; ie none during the lean
> years

Yer right, and a load of use before 1900 is. So were mine, but they probably
had something to do with king Richard I back in 1200 and yours probably have
something to do with the Normans as well.

> (1910-50) and this pattern seems (by casual observation) to repeat
> amongst
> all Greeks. King David had red hair and there are some red haired
> Arabs.

King David is a fictitious character and even if he is based on a real
person his ancestors came from Anatolia not Palestine so would have no
connection with Arabs. If there are red haired Arabs then they are probably
Scythes. Read Herodotus.

> I've seen blond Arab toddlers on NYC Transit and as much as is visible
> of

Yer, yer.... in NYC. Then they are not pure Arabs but interbred. There are
Lebanese who are blond but Lebanese are not Arabs, and anyway their
blondness probably has something to so with Richard I as well.

> their mothers seems dark haired. There are enough writings of fair
> haired
> ancient Greeks to make some sicko white supremacists web cites claim a
> number

The ancient Greeks bleached their hair blond with lemon juice. Any inherited
blondness was already in Greece more than 7000 years ago with the M170 P37
HgI1b linage since that's how long it takes to form a sub linage, and was
probably recessive several millennia before classical times.

> of them were "nordic" or "Alpine" (actually the part of Greece my family
> is
> from, the Pindus Mts, is part of the Alps, but this was only
> acknowledged
> after Greece joined the EU) and that they no longer exist.

And which Alps would this be. Pindus is part of the Balkans range.

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Re: Blond Child, Brownhaired Adult

2006-09-05T07:05:42Z

Yer right, and a load of use before 1900 is. So were mine, but they probably
had something to do with king Richard I back in 1200 and yours probably have
something to do with the Normans as well.

> (1910-50) and this pattern seems (by casual observation) to repeat
> amongst
> all Greeks. King David had red hair and there are some red haired
> Arabs.

King David is a fictitious character and even if he is based on a real
person his ancestors came from Anatolia not Palestine so would have no
connection with Arabs. If there are red haired Arabs then they are probably
Scythes. Read Herodotus.

> I've seen blond Arab toddlers on NYC Transit and as much as is visible
> of

Yer, yer.... in NYC. Then they are not pure Arabs but interbred. There are
Lebanese who are blond but Lebanese are not Arabs, and anyway their
blondness probably has something to so with Richard I as well.

> their mothers seems dark haired. There are enough writings of fair
> haired
> ancient Greeks to make some sicko white supremacists web cites claim a
> number

The ancient Greeks bleached their hair blond with lemon juice. Any inherited
blondness was already in Greece more than 7000 years ago with the M170 P37
HgI1b linage since that's how long it takes to form a sub linage, and was
probably recessive several millennia before classical times.

> of them were "nordic" or "Alpine" (actually the part of Greece my family
> is
> from, the Pindus Mts, is part of the Alps, but this was only
> acknowledged
> after Greece joined the EU) and that they no longer exist.

And which Alps would this be. Pindus is part of the Balkans range.

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[Bioforum] Re: Blond Child, Brownhaired Adult

2006-09-05T00:50:19Z

<vjp2.at@...> wrote in message
news:edirbh$f9h$1@......
> What happens when a blond child has dark hair as an adult? In the
> largest
> Greek parish in the USA (St Nik, Flushing, NY) half the kids going
> for
> communion are blond and both their parents have black hair. ...

Look up the term "tow-head". Actually, I just did, and it doesn't help.

Anecdotally... children will have very blond hair that may darken as they
get older.

It is very common, and not very strange. My mother was very blond as a
child, but had brown hair when she died. I thought that my hair would
darken, but it has stayed a fairly fair red (also known as strawberry
blond). My siblings both have pale brown hair, which has turned gray by the
time they were 40 (my sister keeps hers brunette with the use of hair dye).

Then I looked at my kids... all had blond hair as toddlers. As teenagers
one has light red hair (like me!), one has pale brown hair (like her aunt
and uncle!), and one is still blond!

Anyway, check this out (though it is not very scientific),
http://en.wikipedia.org/wiki/Blond .... with this quote: "Blond hair is
common in infants and children, so much so that the term "baby blond" is
often used for very light-colored hair. Babies may be born with blond hair
even among groups where adults rarely have blond hair, although such natal
hair usually falls out quickly. Blond hair tends to turn darker with age,
and many children born blond turn from anything between a light brown to
even black before or during their teenage years."

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Re: Blond Child, Brownhaired Adult

2006-09-05T00:50:19Z

<vjp2.at@...> wrote in message
news:edirbh$f9h$1@......
> What happens when a blond child has dark hair as an adult? In the
> largest
> Greek parish in the USA (St Nik, Flushing, NY) half the kids going
> for
> communion are blond and both their parents have black hair. ...

Look up the term "tow-head". Actually, I just did, and it doesn't help.

Anecdotally... children will have very blond hair that may darken as they
get older.

It is very common, and not very strange. My mother was very blond as a
child, but had brown hair when she died. I thought that my hair would
darken, but it has stayed a fairly fair red (also known as strawberry
blond). My siblings both have pale brown hair, which has turned gray by the
time they were 40 (my sister keeps hers brunette with the use of hair dye).

Then I looked at my kids... all had blond hair as toddlers. As teenagers
one has light red hair (like me!), one has pale brown hair (like her aunt
and uncle!), and one is still blond!

Anyway, check this out (though it is not very scientific),
http://en.wikipedia.org/wiki/Blond .... with this quote: "Blond hair is
common in infants and children, so much so that the term "baby blond" is
often used for very light-colored hair. Babies may be born with blond hair
even among groups where adults rarely have blond hair, although such natal
hair usually falls out quickly. Blond hair tends to turn darker with age,
and many children born blond turn from anything between a light brown to
even black before or during their teenage years."

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Beefalo and Sturgeon

2006-07-04T08:32:10Z

Steve,

Recently, I found your posting of doing some cytogenetic work on tissue samples of Beefalo. Although your posting was two years old, I am most interested in how you made out in following the inheritance trail of Bison and Bovine interbreeding.

If this is still of interest to you I may have some contributing information that I may be able to share.

Probably one of the most frustrating facts of Beefalo, and Bison Hybrid breeding, is Bison Markers via DNA testing. Some hybrids have Markers, others don't. This doesn't mean they don't contain bison, it's just we lack complete genome sequencing to find it. At this point, that is a very expensive undertaking.

If you are still researching the subject, perhaps my rudementary findings may be of benefit.

Cordially,

Jon Nichols

Jon Nichols Co. LLC

720 Washington St.

Woodland, Wa 98674

jonnichols@...

360-225-0645 ph/fx

PS you'll find attached a picture of my half bison x Charolais Bull "Bold Venture".

boldventure3.JPG (57K) Download Attachment

RECYCLE your used TYVEK coverall garments- we offer to buy them!

2006-06-15T09:54:03Z

Hello,

I am just checking around looking for someone who buys used TYVEK coverall garments. I called the phone number you have listed but it appears the number is no longer in service.

If you are interested please call me at (732) 249-3250 ext. 586 or email aaron@....

Tahnks

Aaron Wilson

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Admin: test posting3

2006-06-03T15:09:53Z

Dear readers,

Please ignore this test message, Bionet is switching Usenet servers
(news.indiana.edu is dying, news.purdue.edu is alive and well).
Test#3

- Don Gilbert

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Admin: test posting2

2006-06-03T14:46:07Z

Dear readers,

Please ignore this test message, Bionet is switching Usenet servers
(news.indiana.edu is dying, news.purdue.edu is alive and well).
Test#2

- Don Gilbert

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Admin: test posting

2006-06-03T13:38:04Z

Dear readers,

Please ignore this test message, Bionet is switching Usenet servers
(news.indiana.edu is dying, news.purdue.edu is alive and well).

- Don Gilbert

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APPLIED COMPUTATIONAL GENOMICS COURSE

2006-05-30T12:01:19Z

Genome Canada
APPLIED COMPUTATIONAL GENOMICS COURSE

September 8-14, 2006, University of Manitoba
Winnipeg, Manitoba, Canada

(International attendees welcome!)
------------------------------------------------------

Bioinformatics in the post-genomic era requires the analysis of
large and diverse datasets using automated tools. While
many Web-based tools are available to the lab researcher,
the Web is awkward for tasks beyond single-sequence annotation.
Researchers need to become productive in a server-based
Unix environment with its wealth of scripting and automation
tools. Even at an entry-level, this can be an intimidating
endeavor. The Genome Canada Bioinformatics Platform is
empowering researchers by teaching a hands-on course,
with lectures and tutorials presented by a panel of
experts. The course uses tools and services available
through the Genome Canada Bioinformatics Platform.
Most tools used are open-source, and can be freely
downloaded for use at one's home institution.
Topics include (tentative):

Becoming a power user
o Basic Unix skills on a network-centric desktop
o BIRCH: Working with sequence datasets on a comprehensive bioinformatics
system
o BIRCH: Creating your own in-house bioinformatics system

Creating automated data pipelines
o Perl scripting: Quick automation of data analysis tasks and utilization
of web services
o BioPerl; Object-oriented Perl; Data warehousing - the SeqHound API
o BioMOBY: a transparent software layer that automatically finds and uses
web services

High throughput genome annotation
o TimeLogic Decypher and Paracel Gene Matcher
o MAGPIE, BLUEJAY : Automated genome analysis, annotation and visualization
o OSPREY: High-throughput oligonucleotide design

Canadian Bioinformatics Help Desk

Secure use of remote bioinformatics systems:

o command line: ssh, sftp, scp, tar, gzip
o remote desktop: VNC

For more information about this workshop go to:

http://www.gcbioinformatics.ca/training

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'Artificial Meiosis' query

2006-05-15T00:12:58Z

Hi,

I doubt this email is still valid. I googled a posting to an email list you
wrote in 1997, asking about what technology there might be to create
'artificial meiosis' in other cell to fertilise an egg. I am looking for
that exact information now for my own situation. Wondering if you found
anything, or have any leads.

thanx,
Eli

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Probes

2006-03-24T01:11:52Z

I'm interested in mouse Y- and X-chromosome specific probes for chromosome
fluorescence in situ hybridization. I want to label this probes with various
fluorescent dyes, so I would be very pleased, if I could get any clones with
these probes.
Any help is requested.

Thank you in advance,

Elsa

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conferences

2006-03-16T17:34:43Z

Dear Chromosomers,

Conference information from plant chromosomes mailing list.

1) http://www.icgs-congress.org/
Second Congress:
International Cytogenetics and Genome Society
and
Digital Scientific UK SmartCapture Users’ Meeting
CANTERBURY ‘06

2) http://www.icc-2007.com/
16th International Chromosome Conference (ICC-2007)
(25-29 August 2007, RAI Conference Centre, Amsterdam, the Netherlands)

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MCF7 and MDA-MB-231 polymorphisms

2006-03-07T10:23:03Z

Hi,

I need to find the polymorphisms/mutations in MCF7 and MDA-MB-231 tumor cell lines. Could anyone suggest a way, or if you know, would you tell me some of these polymorphisms?

Thanks,

Emre

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Wanted: Research Associate / Application Specialist - Cytogenetics BOSTON MA

2006-02-01T05:24:40Z

Research Associate / Application Specialist - Cytogenetics

Living Microsystems is a startup company in Boston, MA, seeking
exceptional talent to help develop a non-invasive application that
provide pregnant women with accurate, and comprehensive prenatal
clinical knowledge in the first trimester of pregnancy. Living
Microsystems, Inc. is currently seeking to fill a position for a
Research Associate / Application Specialist Cytogenetics.

Responsibilities:

The candidate's primary responsibility will be to perform fluorescence
and immunohistochemistry staining of blood samples and support the
collection, cell culture and in vitro assay of blood cells. The
candidate will also perform blood processing experiments using
microfluidic systems and analyze data. Experience in sterile cell
culture procedures, cell processing is needed. Candidates must have a
sound understanding of basic techniques in cell and molecular biology
and biochemistry. Familiarity with brightfield/fluorescence
microscopy, fluorescence in-situ hybridization (FISH), PCR and
hematology are desired. The candidate must be a self-starter, well
organized and be able to work in a multidisciplinary team environment.
Excellent interpersonal, organizational and communication skills are
essential.

Requirements:

BS in biology, pharmacology, biochemistry, or a related discipline. 0-2
years experience in academic research and/or pharmaceutical industry is
desired.

Interested candidates should send a resume AND cover letter to:

Human Resources
Living Microsystems, Inc.
8 St. Mary's Street
Boston, MA 02215
Fax: (617) 353-1912
Email: hr@...

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Artificial meiosis

2005-12-01T20:41:29Z

Hi,

I doubt this email is still valid. I googled a posting to an email list you
wrote in 1997, asking about what technology there might be to create
'artificial meiosis' in other cell to fertilise an egg. I am looking for
that exact information now for my own situation. Wondering if you found
anything, or have any leads.

thanx,
Eli

------------=_438FD081.224B3F76--

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