Nabble - Bio.net - Neur-sci

Re: Heka amplifier problem

2009-12-11T14:01:55Z

I've never seen an error like that.

Do you still get it when you have a model cell plugged into the
headstage or just a resistor between the headstage earth and the
signal pin? What about if you unplug the headstage from the back of
the amp? I've seen something similar that was caused by a broken
headstage. When you unplugged the headstage, the amp started behaving
again.

I'm also wondering, are you sure it is saying "LO BAT". Just because
A's and T's are are hard to write on your standard LCD.

On Dec 11, 9:27 am, Claudio Elgueta Zuñiga <claudi...@...>
wrote:

> Hi friends:
>
> My patch clamp amplifier, a HEKA EPC 7 plus, has completely gone
> mad.The clipping LED is constantly on, and in the LCD displays a message "LO
> BAT" and numbers that doesn´t make sense.
>
> Has anybody experienced this problem. Any battery inside this amplifier?
> Obviously this happens now that I have to get some results for the next
> week.
>
> I have unplugged everything except the power cable.
>
> Thandks in advance, Claudio.
>
> --
> Claudio Andrés Elgueta Zuñiga
> Licenciado en bioquímica, Universidad de Chile
> Programa Doctorado en ciencias, mención neurociencias, Universidad de
> Valparaíso.
> Facultad de ciencias, Universidad de Valparaíso.
> Gran Bretaña 1111, Playa Ancha, Valparaíso.
> Fono: (52)-32-2508186
> mail: claudi...@...

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Re: Heka amplifier problem

2009-12-11T07:39:06Z

On Dec 10, 3:27 pm, Claudio Elgueta Zuñiga <claudi...@...>
wrote:

Have you asked the manufacturer?

http://www.heka.com/

--
Joe
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Heka amplifier problem

2009-12-10T12:27:05Z

Hi friends:

My patch clamp amplifier, a HEKA EPC 7 plus, has completely gone
mad.The clipping LED is constantly on, and in the LCD displays a message "LO
BAT" and numbers that doesn´t make sense.

Has anybody experienced this problem. Any battery inside this amplifier?
Obviously this happens now that I have to get some results for the next
week.

I have unplugged everything except the power cable.

Thandks in advance, Claudio.

--
Claudio Andrés Elgueta Zuñiga
Licenciado en bioquímica, Universidad de Chile
Programa Doctorado en ciencias, mención neurociencias, Universidad de
Valparaíso.
Facultad de ciencias, Universidad de Valparaíso.
Gran Bretaña 1111, Playa Ancha, Valparaíso.
Fono: (52)-32-2508186
mail: claudioez@...
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Bioprotocols online

2009-12-07T17:07:51Z

Sciclips has launched a unique database of bioprotocols for
researchers. Researchers will have free access to these bioprotocols
which have been extracted from published journal articles and patents/
patent applications. We are the first to list protocols from published
US patents, US patent and WO (PCT) applications. We have thousands of
protocols on molecular biology, proteomics, biological imaging,
virology, immunology, stem cells, drug Discovery, immunoassays, cell
biology, epigenetics, genomics, neurosciecne, plant biology,
microbiology, tissue microarrays and more. In addition to this, we
have also listed new sections on high throughput screening (HTS) and
biopharmaceutical assay protocols. All the protocols are linked to the
articles or patent/patent applications. All the protocols are linked
to the articles or patent/patent applications.. Please follow this
link to see the complete list of our bioprotocols online:
http://www.sciclips.com/sciclips/bio-protocols.do
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NUCLEAR PROTEIN

2009-12-04T09:11:03Z

Hi everyone,
I'm studying a nuclear protein and I would like to overexpress it. Someone
provided me a N-terminal FLAG plasmid. Do you think that the FLAG would hide
the nuclear localization sequence?
thank you very much!
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Study Abroad Programs in Neuroscience and Biology

2009-12-02T18:21:49Z

Hi -

Where can I get a comprehensive list of study abroad programs in
neuroscience and biology?

I'm an undergraduate student in the United States.

Thanks -

Katharine Dickson

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Inducers of CREB phosphorylation

2009-12-01T10:30:21Z

There are a number of chemicals that induce phosphoyrlation of CREB, but
I've been unable to find a definitive list. I'm particularly interested in
drugs that induce CREB phosphorylation in the hippocampus. Does anyone
happen to know where I might find such a list?

TIA

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Re: Sensory recognition?

2009-11-30T09:35:20Z

On Nov 30, 11:25 am, Bill <connelly.b...@...> wrote:

> If by biochemical, you mean nutrient, then there is no simple answer
> to this. (or if there was, the answer would be, we don't know). There
> are numerous pathways, involving numerous parts of the brain (not just
> the hypothalamus). The most well understood (as far as I am aware) is
> the selection for carbohydrates and amino acids. I believe the
> carbohydrate selection involves the hypothalamus, and glucose (ATP)
> sensing neurons releasing neuropeptide Y. Diets lacking essential
> amino acid are sensed in the piriform cortex (independent of the sense
> of smell or taste) by a lack of particular tRNA, which then activates
> a complex downstream pathway.
>
> On Nov 30, 12:55 am, Kumar <lordshiva5...@...> wrote:
>
>
>
> > Hello,
>
> > Simply, I want to know, how our neurological system sense
> > defficiencies & excessivness of any bio-chemical & how it react on
> > such sensation?
>
> > Best wishes.- Hide quoted text -
>
> - Show quoted text -

Does brain enhance physiological activities if it is sensed weak
stimuli & resist if sensed strong stimuli?

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Re: Basic question about electrical currents in EEG

2009-11-30T09:29:12Z

Look at displacement current:

http://en.wikipedia.org/wiki/Displacement_current

particularly, note that there are two parts: one resulting from the change
of the electric field, and another from polarization.

cwenhoo wrote:

>>From Luck's book, p.32:
>
> "When a dipole is present in a conductive medium such as the brain,
> current is conducted throughout that medium until it reaches the
> surface...Electricity does not just run directly between two poles of
> a dipole in a conductive medium, but instead spreads out through the
> conductor."
>
> "Another important point is that electricity travels at nearly the
> speed of light. For all practical purposes, the voltages recorded at
> the scalp reflect what is happening in the brain at the same moment in
> time."
>
> My question is, what generates this current flow? I mean I can
> understand if the conductive medium is a piece of metal, then a dipole
> results in direct movement of electrons.
>
> But what about the brain? What is even more confusing to me is that
> action potentials are not even near the speed of light, so how can
> this current resulting from the dipoles in the brain travel that fast?
> _______________________________________________
> Neur-sci mailing list
> Neur-sci@...
> http://www.bio.net/biomail/listinfo/neur-sci
>
>

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Re: Basic question about electrical currents in EEG

2009-11-30T08:43:27Z

On Mon, 30 Nov 2009 00:38:42 -0800 (PST), cwenhoo
<ilangobi@...> wrote:

>From Luck's book, p.32:
>
>"When a dipole is present in a conductive medium such as the brain,
>current is conducted throughout that medium until it reaches the
>surface...Electricity does not just run directly between two poles of
>a dipole in a conductive medium, but instead spreads out through the
>conductor."
>
>"Another important point is that electricity travels at nearly the
>speed of light. For all practical purposes, the voltages recorded at
>the scalp reflect what is happening in the brain at the same moment in
>time."
>
>My question is, what generates this current flow? I mean I can
>understand if the conductive medium is a piece of metal, then a dipole
>results in direct movement of electrons.

The dipoles are the neurons which, when activated, have
different voltages across different parts of their surface.

>But what about the brain? What is even more confusing to me is that
>action potentials are not even near the speed of light, so how can
>this current resulting from the dipoles in the brain travel that fast?

Action potentials are slowed by capacitance and by the time
taken for their underlying mechanisms. Intra-axonal passive
current flow occurs at a rate equivalent to a substantial
proportion of the speed of light.

Kal
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Basic question about electrical currents in EEG

2009-11-30T00:38:42Z

>From Luck's book, p.32:

"When a dipole is present in a conductive medium such as the brain,
current is conducted throughout that medium until it reaches the
surface...Electricity does not just run directly between two poles of
a dipole in a conductive medium, but instead spreads out through the
conductor."

"Another important point is that electricity travels at nearly the
speed of light. For all practical purposes, the voltages recorded at
the scalp reflect what is happening in the brain at the same moment in
time."

My question is, what generates this current flow? I mean I can
understand if the conductive medium is a piece of metal, then a dipole
results in direct movement of electrons.

But what about the brain? What is even more confusing to me is that
action potentials are not even near the speed of light, so how can
this current resulting from the dipoles in the brain travel that fast?
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Re: Sensory recognition?

2009-11-29T22:25:28Z

If by biochemical, you mean nutrient, then there is no simple answer
to this. (or if there was, the answer would be, we don't know). There
are numerous pathways, involving numerous parts of the brain (not just
the hypothalamus). The most well understood (as far as I am aware) is
the selection for carbohydrates and amino acids. I believe the
carbohydrate selection involves the hypothalamus, and glucose (ATP)
sensing neurons releasing neuropeptide Y. Diets lacking essential
amino acid are sensed in the piriform cortex (independent of the sense
of smell or taste) by a lack of particular tRNA, which then activates
a complex downstream pathway.

On Nov 30, 12:55 am, Kumar <lordshiva5...@...> wrote:
> Hello,
>
> Simply, I want to know, how our neurological system sense
> defficiencies & excessivness of any bio-chemical & how it react on
> such sensation?
>
> Best wishes.

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Re: The definition of latency?

2009-11-27T06:29:37Z

On Thu, 26 Nov 2009 23:08:58 -0800 (PST), Bill
<connelly.bill@...> wrote:

>Hi,
>
>If it wasn't explicitly stated, how do you think latency is
>calculated? From the time from the stimulus artifact (or presynaptic
>action potential) to the peak of the synaptic event? To the start of
>the synaptic event? To the rise-10% of the synaptic event?

Since "latency" is vaguely defined as the interval from stimulus to
response, you have to explicitly state the details, probably in
"Materials and Methods". If changes in latency are what is important,
it doesn't really matter just when you begin or when you end timing
(assuming the changes are due to factors in the middle, not at the
ends) as long as you are consistent in measuring.

There are still ambiguities in the definition even if the questions
you pose are fully answered. For example, is the synaptic "event" you
are recording a synaptic potential or is it synaptic current? The
time of peak response differs greatly in these cases as does the
observable time that it starts -- synaptic current being earlier than
potential because of membrane capacitance and longitudinal current
(cable effects). Where is the stimulus located? is presynaptic
action potential propagation a factor in the response latency?

So, all in all, if the fine details of latnecy are important you have
to know all the details. But that is rarely the case and it is
changes in latency that are of interest.

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The definition of latency?

2009-11-26T23:08:58Z

Hi,

If it wasn't explicitly stated, how do you think latency is
calculated? From the time from the stimulus artifact (or presynaptic
action potential) to the peak of the synaptic event? To the start of
the synaptic event? To the rise-10% of the synaptic event?
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Re: do the brain details tour

2009-11-22T07:16:30Z

On Sun, 22 Nov 2009 14:46:06 +0100, Mervyn van Kuyen <mylab@...>
wrote:

>Hello everyone,
>
>if you're interested in a quick tour around the brain visit:
>
>http://www.xs4all.nl/~mylab/library/brain_home/brain.htm
>
>Greetz

Interesting but lots of little errors in labelling.

Kal

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do the brain details tour

2009-11-22T05:46:06Z

Hello everyone,

if you're interested in a quick tour around the brain visit:

http://www.xs4all.nl/~mylab/library/brain_home/brain.htm

Greetz

Mervyn
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BICS 2010 - Call for papers, workshops and tutorials

2009-11-21T11:29:03Z

*We apologize if you receive multiple copies of this message.

==============================================================================

____ _____ _____ _____ ___ ___ __ ___
| _ \_ _/ ____|/ ____| |__ \ / _ \/_ |/ _ \
| |_) || || | | (___ ) | | | || | | | |
| _ < | || | \___ \ / /| | | || | | | |
| |_) || || |____ ____) | / /_| |_| || | |_| |
|____/_____\_____|_____/ |____|\___/ |_|\___/

BRAIN-INSPIRED COGNITIVE SYSTEMS CONFERENCE

Madrid, Spain, July 14-16, 2010

www.bicsconference.org
Ricardo Sanz, General Chair
Sponsored by ICSC

==============================================================================

BICS 2010 is a multitrack conference organised around four strongly related
symposia (NC 2010, BIS 2010, CNS 2010 and MoC 2010). The three previous BICS
conferences were BICS 2008 (Sao Luis, Brasil), BICS 2006 (Lesbos, Greece) and
BICS 2004 (Stirling, UK).

------------------------------------------------------------------------------
Conference Symposia
------------------------------------------------------------------------------

Sixth International ICSC Symposium on Neural Computation (NC 2010)
Fifth International ICSC Symposium on Biologically Inspired Systems (BIS 2010)
Fourth International ICSC Symposium on Cognitive Neuroscience (CNS 2010)
Third International ICSC Symposium on Models of Consciousness (MoC 2010)

------------------------------------------------------------------------------
Motivation
------------------------------------------------------------------------------

Brain Inspired Cognitive Systems - BICS 2010 aims to bring together leading
scientists and engineers who use analytic and synthetic methods both to
understand the astonishing processing properties of biological systems and,
specifically those of the living brain, and to exploit such knowledge to
advance engineering methods for building artificial systems with higher levels
of cognitive competence.

BICS 2010 is a meeting point of cognitive systems engineers and brain
scientists where cross-domain ideas are fostered in the hope of getting new
emerging insights on the nature, operation and extractable capabilities of
brains. This multiple approach is necessary because the progressively more
accurate data about brains is producing a growing need of both a quantitative
and theoretical understanding and an associated capacity to manipulate this
data and translate it into engineering applications rooted in sound theories.

BICS 2010 is intended for both researchers that aim to build brain inspired
systems with higher cognitive competences, and as well to life scientists who
use and develop mathematical and engineering approaches for a better
understanding of complex biological systems like the brain.

BICS 2010 is organized around four major interlaced focal symposia that are
organized into patterns that encourage cross-fertilization across the symposia
topics. This emphasizes the role of BICS as a major meeting point for
researchers and practitioners in the areas of biological and artificial
cognitive systems. Debates across disciplines will enrich researchers with
complementary perspectives from diverse scientific fields.

------------------------------------------------------------------------------
Call for Workshops and Tutorials
------------------------------------------------------------------------------

The Organizing Committee for BICS 2010 requests proposals for a full or half
day workshop or tutorial, to be held on Tuesday, July 13, 2010 at the
Technical University of Madrid, Madrid, Spain. This day of workshops and
tutorials will precede the main conference.

The workshops and tutorials have consistently provided high-quality,
topically-focused forums for researchers at the forefront of basic and applied
research in brain inspired cognitive systems. Workshops should be focused on
interactions of participants to exchange new ideas and explore new directions
in research. Tutorials should provide self-contained descriptions of
established research topics.

The primary criteria for selection are anticipated level of interest, impact,
novelty or creativity, and technical background of presenters.

We request that workshop and tutorial organizers initially email a brief,
single-paragraph description of the proposed topic and a list of organizers by
December 10, 2009 to the BICS Program manager at ipc@....

A template for the final proposal of approximately 3 pages will be mailed to
all interested parties. The full proposal submission should include a title,
an abstract and a description of the proposed content, a tentative schedule,
and the expected requirements for space and equipment. Full proposals for
review will be due by December 10, 2009. All decisions will be made by January
15, 2010.

------------------------------------------------------------------------------
Dates
------------------------------------------------------------------------------

Conference: July 14-16, 2010
Workshops and tutorials: July 13, 2010

Paper submission

Submission of contributions: December 29, 2009
Notification of acceptance: March 10, 2010
Final contributions due: May 15, 2010

Workshops and Tutorials submission

Submission of proposals: December 29, 2009
Notification of acceptance: January 15, 2010

------------------------------------------------------------------------------
Conference Publications
------------------------------------------------------------------------------

All accepted papers will be included in the Conference Proceedings, which will
be published in electronic format. Attendant authors will receive a copy of them
on CD.

* BICS'10 book by Springer
Authors of selected papers will be invited to submit an extended version of them
after the conference, to be included as book chapters in the BICS'10 book to be
published by Springer.

* Special Issue of Cognitive Computation
A post-conference Special Issue of the journal Cognitive Computation will also
be published by Springer with extended versions of selected BICS'2010 papers
chapters and invited contributions.

* Special Issue of the International Journal of Machine Consciousness
A post-conference Special Issue of the International Journal of Machine
Consciousness will also be published with extended versions of selected
contributions to the Symposium on Models of Consciousness of BICS'10.

------------------------------------------------------------------------------
Venue
------------------------------------------------------------------------------

The conference will be held at the Escuela Superior de Ingenieros Industriales
of the Technical University of Madrid (UPM ETSII).

Address: Jose Gutierrez Abascal 2
28006 Madrid
Spain

Geo:lat=40.4404 lon=-3.6902

------------------------------------------------------------------------------
Conference Scope
------------------------------------------------------------------------------

Neural Computation (NC)

NeuroComputational (NC) Systems · NC Hybrid Systems · NC Learning · NC Control
Systems · NC Signal Processing · NC Architectures · NC Devices · NC Perception
and Pattern Classifiers · Support Vector Machines · Fuzzy or Neuro-Fuzzy
Systems · Evolutionary Neural Networks · Biological Neural Network Models · NC
Applications

Biologically Inspired Systems (BIS)

Brain Inspired (BI) Systems · BI Vision · BI Audition and sound processing · BI
Other sensory modalities · BI Motion processing · BI Robotics · BI Adaptive and
Control systems · BI Evolutionary systems · BI Oscillatory systems · BI Signal
processing · BI Learning · Neuromorphic systems

Cognitive Neuroscience (CNS)

CN of vision · CN of non-vision sensory modalities · CN of volition · Systems
Neuroscience · Attentional Mechanisms · Affective Systems · Language · Cortical
Models · Sub-Cortical Models · Cerebellar Models · Neural correlates

Models of consciousness (MoC)

World awareness · Self-awareness · Imagination· Qualia models · Virtual
Machine Approaches · Formal Models of Consciousness · Control Theoretical
Models · Developmental/Infant Models · Will and Volition · Emotion and Affect
Philosophical implications · Neurophysiological Grounding · Enactive
approaches · Heterophenomenology · Analytic/Synthetic phenomenology

------------------------------------------------------------------------------
Program Committee
------------------------------------------------------------------------------

Jaime Gómez (Technical University of Madrid), Chair of the PC

Amir Hussain (University of Stirling, UK), NC Chair
Leslie Smith (University of Stirling, UK), BIS Chair
Igor Aleksander (Imperial College, UK), CNS Chair
Antonio Chella (University of Palermo, UK), MoC Chair

David Gamez (Imperial College, London, UK)
Hugo Gravato Marques (University of Essex, UK)
Alexei Samsonovich (George Mason University, VA, USA)
Raul Arrabales (Universidad Carlos III, Madrid, Spain)
Pentti Haikonen (University of Illinois, Springfield, IL, USA)
Tom Ziemke (University of Skövde, Sweden)
David Balduzzi (University of Wisconsin, WI, USA)
Riccardo Manzotti (IULM, Milan, Italy)
James Albus (George Mason University, VA, USA)
James Austin (Cybula Ltd, UK)
Giacomo Indiveri (University of Zurich, Switzerland)
Alister Hamilton (University of Edinburgh, UK)
F. Claire Rind (Newcastle University, UK)
Sue Denham (University of Plymouth, UK)
Philip Hafliger (University of Oslo, Norway)
David Windridge (University of Surrey, UK)
Luis Rocha (Indiana University, Bloomington, USA)
Shun-ichi Amari (RIKEN Brain Science Institute, Japan)
Jose C. Principe (University of Florida, USA)
Professor Ron Sun (Rensselaer Polytechnic Institute, USA)
Anil K Seth (University of Sussex, UK)
Bernard Widrow (Stanford University, USA)
Stephen Grossberg (Boston University, USA)
Umamaheshwari Ramamurthy (University of Memphis, TN, USA)
Hans-Heinrich Bothe (Technical University of Denmark Lyngby, Denmark)
Marcilio Souto (Federal University of Rio Grande do Norte, Brazil)
Irene Macaluso (Trinity College, Dublin, Ireland)
Will Browne (University of Reading, UK)
Petros A. M. Gelepithis (National and Kapodistrian University of Athens, Greece)

------------------------------------------------------------------------------
Organizing Committee
------------------------------------------------------------------------------

Ramon Galán, Chair of the OC

Carlos Hernández
Iñaki Navarro
Manuel Rodríguez
Pascual Campoy
Paloma de la Puente
Adolfo Hernando
Miguel Olivares
Guadalupe Sánchez

------------------------------------------------------------------------------
Contact
------------------------------------------------------------------------------

General requests: info@...
Organization committee: oc@...
Program committee: pc@...

Conference website: www.bicsconference.org
Conference mailist: http://lists.aslab.upm.es/mailman/listinfo/bics
==============================================================================

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Re: neuronal cultures (from Letizia Polito replied by Bill Connelly)

2009-11-19T16:30:04Z

Dear Letizia and Bill,
we had also severe problems with the neurons from rat embryos.
This changed a lot, when we were testing Neurobasal A medium from
Invitrogen (please remember, I do not intend to do a PR show here,
it's only help!!!).
We tried many things, like low oxygen, low osmolarity, sandwich
coverslip culture, astrocyte feeding layer (which seems to be really
great, but we have problems with the layer...), different media from
many companies and suffered through all this, sometimes great
cultures, sometimes only dead cells in the well / dish.
After all we started using this literature-source as background:
Acute Effects of Ethanol on Kainate Receptors with Different Subunit
Compositions, Valenzuela, Cardoso2, JPET March 1, 1999 vol. 288
no. 3 1199-1206
http://jpet.aspetjournals.org/content/288/3/1199.abstract

This has nothing to do with our research, but is providing very good
and stable culture results.

I can provide you our actual protocol, if you want, but this should be
done out of the list.

But remember, that the pattern of morphology/ type of the neurons in
this culture is quite different from embryonal cultures.

Best regards

Thomas

Quoting neur-sci-request@...,
Neur-sci Digest, Vol 54, Issue 6 (Thu 19 Nov 2009 18:05:41 CET):

> 1. Re: neuronal cultures (Bill)
>
>
> ----------------------------------------------------------------------
>
> Message: 1
> Date: Wed, 18 Nov 2009 16:42:53 -0800 (PST)
> From: Bill <connelly.bill@...>
> Subject: [Neuroscience] Re: neuronal cultures
> To: neur-sci@...
> Message-ID:
> <3c551ba0-e7fd-4293-9d66-5298f04bd381@...>
> Content-Type: text/plain; charset=ISO-8859-1
>
> Adult cortical neuronal cell culture? Yes, it is difficult to get any
> live neurons in your cell culture. We always work with either E16-17
> or P1-3. For adult neuronal culture you need to do all kinds of
> dissociation, gradient separation, and neurotrophic stuff (at least in
> my experience). Do some searches for adult neuronal culture methods
> and I think you'll see what I mean.
>
>
> On Nov 14, 9:44Â am, letizia polito <letizia.pol...@...> wrote:
>> Hi,
>> does anyone work with hippocampal or cortical adult neurons? What are the
>> main problems vs embrional or postnatal cultures? It is difficult to have a
>> neuronal preparation not contaminated by microglia?
>> Thank you everyone.
>
>
>
> ------------------------------
>
> _______________________________________________
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>
> End of Neur-sci Digest, Vol 54, Issue 6
> ***************************************
>

--
~~~~~~~~~~~~
Thomas Breitenbach, PostDoc
Dept. of Physiology/ Chemistry; University of Aarhus
Ole Worms Allé00 160, room 115/ Langelandsgade 140, room 1511-221
DK-8000 Aarhus C
phone: +45 8942 2797
fax: +45 8619 6199
mobil: +45 2298 7186
~~~~~~~~~~~~

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Re: neuronal cultures

2009-11-18T16:42:53Z

Adult cortical neuronal cell culture? Yes, it is difficult to get any
live neurons in your cell culture. We always work with either E16-17
or P1-3. For adult neuronal culture you need to do all kinds of
dissociation, gradient separation, and neurotrophic stuff (at least in
my experience). Do some searches for adult neuronal culture methods
and I think you'll see what I mean.

On Nov 14, 9:44 am, letizia polito <letizia.pol...@...> wrote:
> Hi,
> does anyone work with hippocampal or cortical adult neurons? What are the
> main problems vs embrional or postnatal cultures? It is difficult to have a
> neuronal preparation not contaminated by microglia?
> Thank you everyone.

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neuronal cultures

2009-11-13T12:44:16Z

Hi,
does anyone work with hippocampal or cortical adult neurons? What are the
main problems vs embrional or postnatal cultures? It is difficult to have a
neuronal preparation not contaminated by microglia?
Thank you everyone.
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Re: Rv: LTP mouse in submerged chamber

2009-11-12T16:30:16Z

When it comes to the induction of LTP, people report different
kinetics. I don't think you're problem is the flow rate. 2-3 mL/min is
fine. I think the problem is the bubbles. You're causing electrolytic
lessons. The easiest way to stop the bubbles is to use a glass
microelectrode (500kOhm-2MOhm) filled with aCSF as your stimulating
electrode. Your pulses also seem quite strong (and long). You should
be able to evoke pretty good fEPSPs without resorting to such extreme
stimulus strengths. Finally, 100Hz for 1 second? Have you thought of
switching to a theta burst type paradigm? Most people report stronger
and more stable LTP with theta burst type stimuli.

On Oct 23, 1:47 am, Ana Ruiz Nuño <anaruizn...@...> wrote:

> To members to Neur-sci,
>
>
> I am setting up the LTP in mouse hippocampal slices (350 microns) in a submerged chamber. I get the LTP after 30 min but I think I am still having problems with perfusion because I don't get the typical kinetics as you can see in the attachment.
> Some authors get good kinetics in mouse with 2-3ml/min as I got. Others use faster (5-6ml/min) ones, but sometimes it is not very easy to get an equilibrium between perfusion and stability.
> There is another problem with the mouse slice. Although I place the stimulus and recording within 400-500 microms apart, sometimes you get bubbles after the tetanic stimulation and it takes time till dissapear and get the real effect.
>
> I am stimulating and recording in stratum radiatum of the CA1 region. I try to be consistent and the stimulating microelectrode was positioned in the ipsilateral Schaffer collateral-commissural pathway of CA3 area and the recording microelectrode was placed within the stratum radiatum of CA1 area 300-600 microns apart. Synaptic responses were evoked by constant stimulus pulses (0.2 ms, 0.3-2 mA) delivered by bipolar Ni/Cr stimulating electrode.At the beginning of each experiment, test pulses that evoke 40-50% of the maximum EPSP slope.Tetanic stimulation (TS) was a 1-s 100-Hz pulse for induction of LTP. The amount of LTP was quantified 30 min after the train, and was expressed as percent increases in the slope of field EPSPs. Recording chamber at 3 ml/min at 30-32ºC. I also put a piece of lense paper under the slice.
>
> Any suggestions for improving recordings?. Do you think is a reliable recording for publication?. I attach a typical recording.
>
> Thank you for your time in this matter
>
> Ana

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CFP: ISNN2010 (June 6-10, 2010; Shanghai, China)

2009-11-09T02:53:12Z

CALL FOR PAPERS

7th International Symposium on Neural Networks (ISNN2010)
June 6-10, 2010; Shanghai, China

Websites: http://isnn2010.sjtu.edu.cn or http://isnn2010.mae.cuhk.edu.hk

Paper submissions: http://isnn2010.sjtu.edu.cn/login.asp

The Seventh International Symposium on Neural Networks (ISNN 2010)
will be held in Shanghai, following the successes of previous events.
Shanghai is the largest city in China, located in her eastern coast at
the outlet of the Yangtze River. Originally a fishing and textiles
town, Shanghai grew to importance in the 19th century. In 2005
Shanghai became the world's busiest cargo port. The city is an
emerging tourist destination renowned for its historical landmarks
such as the Bund and Xintiandi, its modern and ever-expanding Pudong
skyline including the Oriental Pearl Tower, and its new reputation as
a cosmopolitan center of culture and design. Today, Shanghai is the
largest center of commerce and finance in mainland China, and has been
described as the “showpiece” of the world's fastest-growing economy.
In addition, Shanghai is the venue of forthcoming World Expo 2010 to
take place from May 1 to October 31 (the symposium registration
includes one day tour to the World Expo on June 10).

ISNN 2010 aims to provide a high-level international forum for
scientists, engineers, and educators to present the state of the art
of neural network research and applications in related fields. The
symposium will feature plenary speeches given by world renowned
scholars, regular sessions with broad coverage, and special sessions
focusing on popular topics.

Prospective authors are invited to contribute high-quality papers to
ISNN 2010. In addition, proposals for special sessions within the
technical scopes of the symposium are solicited. Special sessions, to
be organized by internationally recognized experts, aim to bring
together researchers in special focused topics. Papers submitted for
special sessions are to be peer-reviewed with the same criteria used
for the contributed papers. Researchers interested in organizing
special sessions are invited to submit formal proposals to ISNN 2010.
A special session proposal should include the session title, a brief
description of the scope and motivation, names, contact information
and brief biographical information on the organizers.

Authors are invited to submit full-length papers (10 pages maximum) by
the submission deadline through the online submission system.
Potential organizers are also invited to enlist five or more papers
with cohesive topics to form special sessions. The submission of a
paper implies that the paper is original and has not been submitted
under review or copyright-protected elsewhere and will be presented
by an author if accepted. All submitted papers will be refereed by
experts in the field based on the criteria of originality,
significance, quality, and clarity. The authors of accepted papers
will have an opportunity to revise their papers and take consideration
of the referees' comments and suggestions. The ISNN 2010 proceedings
will be published by Springer in its series of Lecture Notes in
Computer Science (EI) and Advances in Intelligent and Soft Computing
(ISTP). Selected good papers will be included in special issues of
several journals such as Neurocomputing, Neural Computation and
Applications, Cognitive Neurodynamics, Cognitive Computation, and
Mathematics and Computers in Simulation. In addition, the
International Neural Network Society (INNS) will offer two best
student paper awards (US$250 each with one-year INNS membership).

************************************************
TOPIC AREAS
************************************************

1. Computational Neuroscience and Cognitive Science
Spiking neurons
Visual and auditory cortex
Neural encoding and decoding
Plasticity and adaptation
Brain imaging
Learning and memory
Inference and reasoning
Perception, emotion and development
Attractor and associative memory
Neurodynamics and complex systems

2. Models, Methods and Inference
Stability and convergence analysis
Neural network models
Supervised learning
Unsupervised learning
Embeddings and manifold learning
Active learning
Statistical and informationtheoretic methods
Kernel methods and support vector machines
Mixture models
Graphical and causal models
Bayesian networks
Topic models
Gaussian processes
Model selection
Matrix/tensor analysis
Structured and relational data
Clustering

3. Vision and Auditory Modelling
Visual perception and modelling
Visual selective attention
Statistical and pattern recognition
Visual coding and representation
Object recognition
Motion and tracking
Natural scene analysis
Auditory perception and modelling
Source separation
Speech recognition and speech synthesis
Speaker identification
Audio and speech retrieval
Music modelling and analysis

4. Control, Robotics and Hardware
Neuromorphic hardware and implementation
Embedded neural networks
Fuzzy neural networks
Cognitive robotics
Developmental robotics
Multi-agent systems and game theory
Reinforcement learning
Planning and decision making
Action and motor control
Visuomotor control

5. Novel Approaches and Applications
Brain-like systems
Adaptive intelligent systems
Brain-computer interfaces
Granular computing
Hybrid intelligent systems
Neuroinformatics and neuroengineering
Bioinformatics
Information retrieval
Data mining and knowledge discovery
Natural language processing

************************************************
IMPORTANT DATES
************************************************

Full paper submission deadline: December 1, 2009
Notification of acceptance: January 1, 2010
Camera-ready copy and author registration: February 1, 2010

For inquiries, please contact the secretariat at isnn2010@...
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Re: Adhesion of tissue slice onto a glass substrate

2009-11-05T17:22:07Z

Hi Vini,

I have two thoughts. The classical way of holding down slices is to
bend a piece of platinum (1mm) into a U shape, and then adhere
(cynoacrylate glue) fine fibers across the U (so it looks like a
harp). Then use that to hold down you slice. I don't fully understand
the geometry of your electrode, but if the platinum causes a short
circuit, you can coat it in cynoacrylate, or by teflon coated wire. If
you're scared of compressing your retina, use a vice (with a flat
gripping face) and a micrometer, and compress the platinum down to the
nominal thickness of a retina, then put the harp on upside down, so
the fibres are only just touching the retina.

You can also try precoating the glass with something like laminin,
poly-L-lysine or a non-organic hydrophobic coating like sylguard. But
if you electrode is base of your chamber, this this won't really be an
option.

Your final option is to drop submersions recording, and use an
interface chamber.

On Oct 24, 6:02 pm, vini <exoticv...@...> wrote:

> Hello,
>
> I am doing an extracellular recording from a mouse retina. I use
> planer metal electrodes on glass. However, the tissue when placed on
> glass and perfused, starts to float in the medium, whatever small the
> perfusion rate I keep. This is a big problem for me because for my
> recordings, I need to have tissue sticking properly on the glass..
>
> I have tried using a filter paper carrier, it still floats :(
>
> Can someone help me in this regard?
>
> Thanks,
>
> Vini.

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FW: Symposium on Disorders of Consciousness Cuba 2010

2009-11-01T08:15:45Z

Dear colleague, the International Symposium on Disorders of =
Consciousness
will be held in Cienfuegos, Cuba, on March 16-18, 2010. This conference =
will
be held in parallel with the National Congress of Neurology at the same
venue (http://promociondeeventos.sld.cu/neurologia2010/).

=20

Please, note that American citizens can legally attend our Symposium =
(read
information below).

=20

We expect to welcome you!!

=20

CALIXTO MACHADO, MD, Ph.D., FAAN

President

International Symposium on Disorders of Consciousness

E-mail: <mailto:braind@...> braind@...

=20

=20

=09

logo

Organized by the IAB Network for the Definition of Death

=20

Dear colleagues,
Since its foundation in 1996, the Definition of Death Network from the
International Association of Bioethics (IAB), has maintained a fruitful
discussion about all medical and ethical issues related to human death,
end-of-life dilemmas, and consciousness disorders.
We have the pleasure of inviting you to attend the International =
Symposium
on Disorders of Consciousness, organized by the International =
Association of
Bioethics, to be held in Cienfuegos, Cuba, on March 16-18, 2010.
The Terry Schiavo, and other famous cases, have raised new controversies
about the diagnosis and management of the persistent vegetative, the
minimally conscious state, etc. Hence, the disorders of consciousness
discussions are actual and permanent subjects for debate in the media =
and
scientific discussion in any forum. Hence, our main goal is to provide a
suitable scientific platform to discuss all topics disorders of
consciousness.
Cubans will sincerely offer you a warm hospitality in Cienfuegos city, =
named
as the Pearl of the South, with a beautiful harbor and an incredible =
blue
sea, will provide the most proper venue to discuss any issue related to
human consciousness.

Sincerely,

Dr. Calixto Machado, MD, PhD
President of the Symposium

=20

MAIN TOPICS

=95 Pathophysiology of consciousness generation
=95 Theories about consciousness in human beings
=95 Coma, persistent vegetative state (PVS), minimally conscious state =
(MCS),
and coma.
=95 Clinical diagnosis of coma, PVS and MCS.
=95 Neuroimaging techniques for assessing coma, PVS and MCS.=20
(MRI, fMRI, MRS, PET, SPECT, QEEG, MEG, etc.)
=95 Neurophysiologic tests for assessing coma, PVS and MCS.
=95 Neurorehabilitation of PVS and MCS..
=95 Neuroprotection.
=95 Neurocritical care and Neuromonitoring
=95 New trends in cerebral cardio-pulmonar-cerebral resuscitation.

=20

INSTRUCTIONS TO SUBMIT AN ABTRACT

You can participate in our Symposium as a delegate, although we =
encourage
you to submit an abstract. Please, carefully read the following =
instructions
before submitting your abstract. Only abstracts submitted in English =
will be
accepted, in order to be published. Abstracts sent in Spanish will not =
be
considered. Submit your abstract in Microsoft Word (2003 or 2007).

=95 Authors' names should be provided in the format "R.S. Alvarez, J.M.
Manero". You should write your first names initials, and your second =
name.
Do not add Dr, Prof, Mr, Mrs, etc. The first name will correspond with =
the
Presenting author.
=95 The title should have a maximum of 150 characters, typed in =
capitals.
=95 Affiliation should be included in line a. If authors=92 affiliations =
are
different, your should indicate them filling b, c, and d lines. The
presenting author=92s email address should be included.
=95 The abstract should have a maximum of 250 words. Any longer and the
abstracts will be truncated or not accepted.
=95 Indicate whether the abstract is intended for oral or poster =
presentation
or either.
=95 The abstract should be structured using the following headings: =
Objective,
Methods, Results, Conclusions, and Keywords (no less than 4 =
keywords).
=95 The abstract should be as informative as possible, including =
statistical
evaluation.
=95 Statements such as "results will be discussed" or "data will be =
presented"
are not acceptable.
=95 Standard abbreviations such as: PVS, MCS, EEG, MEEG, MRI, etc., may =
be
used. Others should be described in full when first mentioned =
followed by
the abbreviation in parenthesis.
=95 Tables may be included, but not photographs, figures or references.

Confirmation of Receipt of Abstracts
=95 You will be sent a notice, via e-mail to confirm that your abstract =
has
been received.=20
=95 If you do not receive a confirmation within two week please contact =
the
Symposium Secretariat.
=95 Abstracts will be reviewed by the Scientific Committee. Some very =
high
quality abstracts offered for oral presentation might be included in
symposia or courses.

Deadline for submission of abstracts: February 15, 2010
Notification of Accepted Abstracts: February 20, 2010

=20

REGISTRATION FEE:

Delegates: 200 Euros
Includes:

=20

=95 Badge=20
=95 Symposium documentation=20
=95 Access to the Symposium activities=20
=95 Certificate of presentation and/or attendance=20
=95 Welcome cocktail and Farewell party=20
=95 Access to the Congress of Neurology Activities

=20

Accompanying persons: 100 Euros
Includes:

=09

=20

=95 Badge=20
=95 Access to the program for accompanying persons
=95 Opening and closing ceremonies=20
=95 Access to the social and cultural activities

=09

=20

=09

For further information contact:

=09

Dr. Calixto Machado, MD, Ph.D.
President
International Symposium on Disorders of Consciousness

Instituto de Neurolog=EDa y Neurocirug=EDa
29 y D, Vedado, Apartado Postal 4268=20
Ciudad de La Habana 10400=20
Tel.: 537-834 5578 Fax: 537-838 3020

E-mail: braind@...
http://www.changesurfer.com/BD=20
http://www.bioethics-international.org/iab-2.0/index.php?show=3Dnetworks =

=09

=20

=09

FOR AMERICAN CITIZENS

=09

It is important to remark that American citizens can legally attend this
Symposium in Cuba under the general license, because this meeting is
organized by the International Association of Bioethics (Network for the
Definition of Death), and Cuba is only the host.
Under the U.S. restrictions, full-time professionals may attend =
professional
meetings or conferences in Cuba organized by an international =
organization
that regularly sponsors meetings or conferences in other countries. This
authorization is provided by a general license in the regulations; the
professional need not make application to the Office of Foreign Assets
Control (OFAC =96 the office within the U.S. Treasury Department which
oversees the regulations). Full time professionals may attend =
international
conferences or meetings which meet its criteria without obtaining any
documentation from the U.S. government.=20
The International Association of Bioethics (IAB) is an international
professional organization based in=20
Queson City in the Philippines, and has organized many international
conferences in other countries over=20
the years.=20
See: =
http://www.bioethics-international.org/iab-0/index.php?show=3Dnetworks=20

=09

=20

=09

For travel arrangement and hotel booking, contact:=20
WILSON INTERNATIONAL SERVICE
4919 S.W. 75 AVENUE
MIAMI, FLA. 33155
TEL. (305) 6626842
FAX (305) 6674417
E-mail: leisyt@...
<file:///\\leisyt@...>=20

=09

=20

=09

=20

=09

=20

=09

=20

=0A--=0A=0AEste mensaje le ha llegado mediante el servicio de correo electronico =
que ofrece Infomed para respaldar el cumplimiento de las misiones del Sistem=
a Nacional de Salud. La persona que envia este correo asume el compromiso de=
usar el servicio a tales fines y cumplir con las regulaciones establecidas=
=0A=0AInfomed: http://www.sld.cu/=0A

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Re: Maths student with much brain missing?

2009-10-26T18:01:12Z

That sounds very much like one of John Lorber's patients. He was a British
neurosurgeon who argued that in some cases there is evidence of massive
neocortical loss without apparent behavioral anomalies. He makes specific
reference to one maths student who had massive tissue loss. Lorber was
generally laughed at for his views but a recent case from France has
resurrected the issue. Raises interesting questions about cerebral
organisation but not about the "mind body problem", whatever that is.

John.

<charlesgriffin@...> wrote in message
news:mailman.98.1255441164.1133.neur-sci@......
Hello Neur-Sci members...

I'm writing a book which involves, among other things, the brain/mind issue.

Some 30 years ago I remember a report (possibly in the New Scientist) about
a maths? student at the University of Birmingham, UK, who, as I recall,
passed his exams, but then became unwell. An x-ray found that he had only a
cortex, and very little or no other brain matter. I remember that the report
contained what seems to have been the x-ray picture of a more or less empty
head.

I moved house some 25 years ago, and the article has got hopelessly lost.

Can anybody help me, please? What I would like most would be an ecopy of the
original article. Failing that, any pukka information or route to
investigate.

Thanks very much indeed for your time.

All best wishes Chas Griffin

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Adhesion of tissue slice onto a glass substrate

2009-10-23T22:02:31Z

Hello,

I am doing an extracellular recording from a mouse retina. I use
planer metal electrodes on glass. However, the tissue when placed on
glass and perfused, starts to float in the medium, whatever small the
perfusion rate I keep. This is a big problem for me because for my
recordings, I need to have tissue sticking properly on the glass..

I have tried using a filter paper carrier, it still floats :(

Can someone help me in this regard?

Thanks,

Vini.
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Update available: impulsing in the nervous system at impulsing.org

2009-10-22T15:01:12Z

Update available: impulsing in the nervous system at
www.impulsing.org

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Rv: LTP mouse in submerged chamber

2009-10-22T05:47:52Z

To members to Neur-sci,

I am setting up the LTP in mouse hippocampal slices (350 microns) in a submerged chamber. I get the LTP after 30 min but I think I am still having problems with perfusion because I don't get the typical kinetics as you can see in the attachment.
Some authors get good kinetics in mouse with 2-3ml/min as I got. Others use faster (5-6ml/min) ones, but sometimes it is not very easy to get an equilibrium between perfusion and stability.
There is another problem with the mouse slice. Although I place the stimulus and recording within 400-500 microms apart, sometimes you get bubbles after the tetanic stimulation and it takes time till dissapear and get the real effect.

I am stimulating and recording in stratum radiatum of the CA1 region. I try to be consistent and the stimulating microelectrode was positioned in the ipsilateral Schaffer collateral-commissural pathway of CA3 area and the recording microelectrode was placed within the stratum radiatum of CA1 area 300-600 microns apart. Synaptic responses were evoked by constant stimulus pulses (0.2 ms, 0.3-2 mA) delivered by bipolar Ni/Cr stimulating electrode.At the beginning of each experiment, test pulses that evoke 40-50% of the maximum EPSP slope.Tetanic stimulation (TS) was a 1-s 100-Hz pulse for induction of LTP. The amount of LTP was quantified 30 min after the train, and was expressed as percent increases in the slope of field EPSPs. Recording chamber at 3 ml/min at 30-32ºC. I also put a piece of lense paper under the slice.

Any suggestions for improving recordings?. Do you think is a reliable recording for publication?. I attach a typical recording.

Thank you for your time in this matter

Ana

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PhD-Position "Investigation of activity-dependent signal integration in neocortical neurons" at the Bernstein Center Freiburg

2009-10-19T05:14:01Z

Phd-Position
Investigation of activity-dependent signal integration in neocortical
neurons

Our lab uses combined intra- and extracellular recordings in rat V1 in vivo,
as well as dynamic photo stimulation of acute brain slices to study network
dynamics in V1 and the influence of dynamical states on the integration of
synaptic input in pyramidal cells. The offered position is funded by the EU
FACETS program (http://facets.kip.uni-heidelberg.de), and should, therein,
contribute to the aspect of experimental characterization of cortical cells
and networks in vivo and in vitro.

The goal of our work is to link the obtained electrophysiological data, in
close collaboration with other groups at the BCCN and within FACETS, to new
models of neocortical networks, aimed to better understand the mechanisms
underlying network dynamics in the cortex.

The phd position is available immediately for 3 years.

We are looking for experimentalists with a solid background in
electrophysiological recording techniques and interest in computational
neuroscience.

Please apply via the online application form:
http://www.bccn2.uni-freiburg.de/p <http://www.bccn2.uni-freiburg.de/phd
_applications/index.php> hd _applications/index.php (Project-ID: FACETS)

-- Dr. Janina Kirsch --
Coordinator for the Teaching & Training Programs
Bernstein Center Freiburg
Albert-Ludwig University of Freiburg
Hansastr. 9a
D - 79104 Freiburg
Germany

Phone: +49 (0) 761 203-9575
Fax: +49 (0) 761 203-9559

Email: kirsch <mailto:kirsch@...> @bcf.uni-freiburg.de
Web: <http://www.bcf.uni-freiburg.de/> www.bcf.uni-freiburg.de

_____

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Re: Re: Question from a student for the list

2009-10-16T14:00:55Z

On the other hand, if you're a smart 'un you'll be wasting time doing a masters. Coz, you could essentially get the hang of "research" in about 6 months, even rocket science is not as difficult as is made out to be.
Then again, perhaps it is a good idea to go for masters, in case you decide after two years that getting a doctorate is a super waste of time (which sometimes it is), you have a degree that allows you credibility and land an equally good job. :)

Good luck!

Polly

--- On Fri, 10/16/09, Bill <connelly.bill@...> wrote:

> From: Bill <connelly.bill@...>
> Subject: [Neuroscience] Re: Question from a student for the list
> To: neur-sci@...
> Date: Friday, October 16, 2009, 3:31 AM
> In the UK and Australia if you enter
> a PhD they are going to expect
> you are research ready. That you understand the topic and
> the methods
> (though you don't have to have practicle experience). 99%
> of the
> people in the PhD stream with you will have already done a
> years
> (either full or part time) worth of research.
>
> If that sounds intimidating, then it sounds like you should
> do a
> masters, and if I were you, I would do my masters in the
> same lab you
> plan to do your PhD in.
>
> On Oct 11, 7:51 am, Katharine Dickson <neurobad...@...>
> wrote:
> > I am an undergrad headed for graduate school to get my
> PhD. The
> > question is what route I'm going to take.
> >
> > It is probable that I am going to end up going to
> graduate school
> > overseas; my top programs, and indeed, most of the
> programs that
> > actually do research in the area that I want to
> research, are located
> > in England, Scotland, and Australia. Knowing how
> their degrees are
> > structured (little to no graduate courses, per se,
> depending on
> > whether you enter with a bachelor's degree or with a
> master's degree,
> > and one can even have zero courses entering with only
> a bachelor's
> > degree), which route do you recommend for maximizing
> the chance that
> > I'll have success in finding a postdoctorate and
> faculty position
> > afterward? If I elect to get a master's degree
> before beginning a
> > PhD, I'll probably remain in the United States until I
> begin my PhD.
> >
> > 1) Straight to doctorate
> > 2) Get a master's degree before starting my doctorate
> >
> > Any opinions or advice are welcome.
> >
> > Katharine Dickson
>
> _______________________________________________
> Neur-sci mailing list
> Neur-sci@...
> http://www.bio.net/biomail/listinfo/neur-sci
>

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Re: Question from a student for the list

2009-10-15T15:01:36Z

In the UK and Australia if you enter a PhD they are going to expect
you are research ready. That you understand the topic and the methods
(though you don't have to have practicle experience). 99% of the
people in the PhD stream with you will have already done a years
(either full or part time) worth of research.

If that sounds intimidating, then it sounds like you should do a
masters, and if I were you, I would do my masters in the same lab you
plan to do your PhD in.

On Oct 11, 7:51 am, Katharine Dickson <neurobad...@...> wrote:

> I am an undergrad headed for graduate school to get my PhD. The
> question is what route I'm going to take.
>
> It is probable that I am going to end up going to graduate school
> overseas; my top programs, and indeed, most of the programs that
> actually do research in the area that I want to research, are located
> in England, Scotland, and Australia. Knowing how their degrees are
> structured (little to no graduate courses, per se, depending on
> whether you enter with a bachelor's degree or with a master's degree,
> and one can even have zero courses entering with only a bachelor's
> degree), which route do you recommend for maximizing the chance that
> I'll have success in finding a postdoctorate and faculty position
> afterward? If I elect to get a master's degree before beginning a
> PhD, I'll probably remain in the United States until I begin my PhD.
>
> 1) Straight to doctorate
> 2) Get a master's degree before starting my doctorate
>
> Any opinions or advice are welcome.
>
> Katharine Dickson

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Re: Maths student with much brain missing?

2009-10-14T19:52:07Z

On Oct 13, 6:09 am, <charlesgrif...@...> wrote:

> Hello Neur-Sci members...
>
> I'm writing a book which involves, among other things, the brain/mind issue.
>
> Some 30 years ago I remember a report (possibly in the New Scientist) about a maths? student at the University of Birmingham, UK, who, as I recall, passed his exams, but then became unwell. An x-ray found that he had only a cortex, and very little or no other brain matter. I remember that the report contained what seems to have been the x-ray picture of a more or less empty head.
>
> I moved house some 25 years ago, and the article has got hopelessly lost.
>
> Can anybody help me, please? What I would like most would be an ecopy of the original article. Failing that, any pukka information or route to investigate.
>
> Thanks very much indeed for your time.
>
> All best wishes Chas Griffin

A little more recently:

http://www.newscientist.com/article/dn12301-man-with-tiny-brain-shocks-doctors.html

--
Joe
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Maths student with much brain missing?

2009-10-13T03:09:33Z

Hello Neur-Sci members...

I'm writing a book which involves, among other things, the brain/mind issue.

Some 30 years ago I remember a report (possibly in the New Scientist) about a maths? student at the University of Birmingham, UK, who, as I recall, passed his exams, but then became unwell. An x-ray found that he had only a cortex, and very little or no other brain matter. I remember that the report contained what seems to have been the x-ray picture of a more or less empty head.

I moved house some 25 years ago, and the article has got hopelessly lost.

Can anybody help me, please? What I would like most would be an ecopy of the original article. Failing that, any pukka information or route to investigate.

Thanks very much indeed for your time.

All best wishes Chas Griffin
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Question from a student for the list

2009-10-10T11:51:28Z

I am an undergrad headed for graduate school to get my PhD. The
question is what route I'm going to take.

It is probable that I am going to end up going to graduate school
overseas; my top programs, and indeed, most of the programs that
actually do research in the area that I want to research, are located
in England, Scotland, and Australia. Knowing how their degrees are
structured (little to no graduate courses, per se, depending on
whether you enter with a bachelor's degree or with a master's degree,
and one can even have zero courses entering with only a bachelor's
degree), which route do you recommend for maximizing the chance that
I'll have success in finding a postdoctorate and faculty position
afterward? If I elect to get a master's degree before beginning a
PhD, I'll probably remain in the United States until I begin my PhD.

1) Straight to doctorate
2) Get a master's degree before starting my doctorate

Any opinions or advice are welcome.

Katharine Dickson

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PhD-Positions in Neuroinformatics, including Computational Neuroscience (Erasmus Mundus Program)

2009-10-07T01:26:36Z

The Erasmus Mundus Joint Doctoral Program "EuroSPIN
<http://www.kth.se/studies/phd/eurospin?l=en_UK> " (European Study Programme
in Neuroinformatics) is inviting applications from students having a solid
background in mathematics, physics, computer sciences, biochemistry or
neuroscience (on a master level or equivalent), in all cases with computer
science skills. Documented interest in research like activities (e.g.
demonstrated in the form of master thesis work, or participation in research
related activities) is of large importance. Also fluency in English is
requested.

Neuroinformatics combines neuroscience and informatics research to develop
and apply computational tools and approaches that are essential for
understanding the structure and function of the brain.
Four partners participate in EuroSPIN:
- <http://www.csc.kth.se/forskning/cb/> KTH Royal Institute of Technology,
Sweden
- <http://www.inf.ed.ac.uk/> University of Edinburg (UoE), UK
- <http://www.ncbs.res.in/> National Centre for Biological Science (NCBS),
India
- <http://www.bccn.uni-freiburg.de> Albert-Ludwigs-Universität Freiburg
(ALUF), Germany
These four partners are all research leaders in the Neuroinformatics field,
but they have complementary strengths. In addition, two associated partners,
the Honda Research Institute and Nordita, participate.

Each student will spend most of the time at two of the partner
<http://www.kth.se/studies/phd/eurospin/partners?l=en_UK> universities, and
also receive a joint (or double) PhD degree following a successful
completion of the studies. The mobility periods, as well as the courses a
student will follow, are tailored individually based on: a) the PhD students
background; b) which constellations of partners that are involved, as well
as c) the specific research project. During the PhD period each student has
one main supervisor from each of the two universities that grant the PhD
degree.

During the application process, the students are asked to indicate their
preferences with regard to constellations of
<http://www.kth.se/studies/phd/eurospin/2.18027?l=en_UK> partners, and also
preferred project ideas/areas can be indicated and motivated.

There are excellent scholarship
<http://www.kth.se/studies/phd/eurospin/scholarships-fees?l=en_UK>
opportunities for students accepted to an Erasmus Mundus Joint Doctorate
programme. A stipend or employment contract will be given to all selected
PhD students during the study time, which is between 3-4 years.

If you are interested, go to our homepage:
http://www.kth.se/studies/phd/eurospin?l=en_UK.
Deadline for Application (non-EU students): December 15, 2009.
Deadline for Application (EU students): about March 2009 (will be
announced).

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