First African Structural Biology Conference

[FASB Organisers]

Are you interested in RATIONAL DRUG DESIGN?


X-ray crystallographic visualization of an inhibitor which is a =
potential drug in the active site of an enzyme done by a group of South =
African researchers

The First African Structural Biology Conference
Macromolecular Structure, Health and Biotechnology in Developing =
Countries

The Wilderness, South Africa
24-27 October 2006


The First African Structural Biology (FASB) conference will be held in =
The Wilderness, South Africa. Structural Biology is fundamental to =
rational drug design and central to the drug discovery process. We are =
fortunate in having a number of speakers who have been successful in =
this area and who have applied their minds to the diseases of the =
developing world.

Expression of interest and registration forms can be submitted online by =
visiting our website:

http://sbio.uct.ac.za/conference

Programme

Tuesday 24 October 2006
2:00 pm
Dr P Mjwara (Department of Science and Technology, South Africa).
3:00 pm
Prof Sir Tom Blundell, FRS (University of Cambridge, UK).
Structural Biology and Modern Drug Discovery.
4:00 pm
Tea
4:20 pm
Prof Wieland Gevers (ASSAf, South Africa)
Introduction of ASSAf Speaker Joachim Frank
4:30 pm
ASSAf Lecture
Dr Joachim Frank (Howard Hughes Medical Institute, USA).
The Ribosome in Motion as seen by Cryo-EM.
5:30 pm
Prof Iain Campbell (University of Oxford, UK).
The role of NMR in structural biology and drug discovery.
6:30 pm
Dinner
7:30 pm
Poster Session
=20
=20
Wednesday 25 October 2006
8:00 am
Dr Gert Vriend (University of Nijmegen, Holland).
Protein Modelling.
9:00 am
Dr Steve Bryant (NCBI, USA).
Protein Classification Methods for NCBI's Conserved Domain Database.
10:00 am
Contributed Papers
10:30 am
Tea
11:00 am
Prof Christian Sommerhoff (University of Munich, Germany).
Parasite-derived Inhibitors of Mast Cell Proteases: Templates for Drug =
Development.
12:00 pm
Prof Ravi Archarya (University of Bath, UK).
Structure based design of new ACE inhibitors through Cape Town (South =
Africa) - Bath (UK) link.
1:00 pm
Lunch
2:30 pm
Dr Rolf Boelens (University Utrecht, Netherlands)
3:30 pm
Bruker Lecture
Dr Rudiger Weisemann (Bruker, Germany)
NMR Spectroscopic Studies of Protein/Ligand interactions.
4:00 pm
Tea
4:20 pm
Contributed Papers
4:40 pm
Contributed Papers
5:00 pm
Contributed Papers
6:30 pm
Dinner
7:30 pm
Posters
=20


=20
Thursday 26 October 2006
8:00 am
Prof James Sacchettini (Texas A&M University, USA).
Combining Structural Genomics and Drug Discovery to Develop New TB =
Drugs.
9:00 am
Dr Peter Kwong (National Institute of Health, USA).
10:00 am
Contributed Papers
10:30 am
Tea
11:00 am
Prof David Rice (University of Sheffield, UK).
>From drugs to herbicides: the impact of structural biology on rational =
design.
12:00 pm
Prof Krishna Murthy (Alabama University, USA).=20
1:00 pm
Lunch
2:30 pm
Canoeing on the Wilderness Lagoon sponsored by Rigaku MSC
6:30 pm
Gala Dinner
7:30 pm
Posters
=20
=20
Friday 27 October 2006
8:00 am
Prof Karolin Luger (Colorado State University, USA).=20
Of nucleosomes, viral hitch-hikers, and chaperones.
9:00 am
Prof Andreas Hoenger (University of Colorado at Boulders, USA).
Structural Investigations into the Interaction between Microtubules and =
Mal3p, an S.pombe Homologue of EB1.
10:00 am
Contributed Papers
10:30 am
Tea
11:00 am
EMBO Lecture
Prof Helen Saibil, FRS (University of London, UK).=20
One Sequence, Two Structures: protein conformational changes that cause =
disease.
12:00 pm
Prof Edward Egelman (University of Virginia, USA).=20
Order, Disorder and Heterogeneity in Helical Polymers.=20
1:00 pm
Lunch
2:30 pm
Prof Igor Polikarpov (University of Sao Paulo, Brazil).
Structural Studies of HIV Proteases of Subtype B and F and their =
Mutants.
3:30 pm
Prof Mamannamana Vijayan (Indian Institute of Science, India).
Structural biology of Mycobacterial Proteins the Indian Scenario.
4:00 pm
Tea
4:20 pm
Dr Frank Von Delft (Structural Genomics Consortium, Oxford UK)
4:40 pm
Dr Bethuel Sehlapelo (Department of Science and Technology, South =
Africa).
5:00 pm
Discussion
6:30 pm
Dinner
7:30 pm
Posters
=20
=20


Conference Organizer:=20
Trevor Sewell
Institute of Infectious Disease and Molecular Medicine
Wolfson Pavilion, Level 3
Faculty of Health Sciences
University of Cape Town
Anzio Road
Observatory,
7925
South Africa Tel.: [phone]
Fax: [phone]
E-mail: sewell@...

Conference Organizing Committee:
Dr Arvind Varsani (arwind@...)
Professor Girish Kotwal (gkotwal@...)
Professor Ed Sturrock (sturrock@...)
Dr Muhammed Sayed (msayed@...)
Dr David Pugh (dpugh@...)
Miss Eulashini Chuntharpursat (eulashini@...)
Mrs Miranda Waldron (mwaldron@...)
                        =20




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