deletin mutation and phenotype expression

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deletin mutation and phenotype expression

by Kanchanadevi k :: Rate this Message:

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 hi everyone


There is one mutant bacterial strain which is mutated by deletion mutation
of particular gene
even after deletion mutation it's reported that this mutant strain can
express that phenotype in minimal amount.

so can any one tell me
how is this possible the gene responsible for particular metabolite is
deleted but still it's produces minimal amount of that metabolite.



kanchan
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Parent Message unknown Re: deletin mutation and phenotype expression

by N10 :: Rate this Message:

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"Bob" <bbx107.XYZ@...> wrote in message
news:poak65dmp4c8d4ahj406nufpfqe28ghtqk@......

> On Fri, 24 Jul 2009 22:53:45 +0530, Kanchanadevi k <kdevik@...>
> wrote:
>
>> hi everyone
>>
>>
>>There is one mutant bacterial strain which is mutated by deletion mutation
>>of particular gene
>>even after deletion mutation it's reported that this mutant strain can
>>express that phenotype in minimal amount.
>>
>>so can any one tell me
>>how is this possible the gene responsible for particular metabolite is
>>deleted but still it's produces minimal amount of that metabolite.
>
>
> It would be best to consider the specific case. Can you give a
> reference for this.
>
> But briefly in general...
>
> Is it really true? Are the analyses correct? Not always easy.
>
> If really true, then there may be a 2nd gene that can compensate. This
> is the case for Lac+ strains of E coli derived after total deletion of
> the original lactase.
>
> bob
>

An interesting question and a good reply by Bob but sadly no response from
the originator...now I cant sleep !


N10


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