sick fish???

[yin alessa]

Dear All,

I had one tank of fish, the males started to get kinky body and become
very short, whereas all the females look very healthy.  Does anybody
know what's going on?

Thanks!

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[yin alessa]

BTW: the fish were just changed from fry food to adult food.  There
are about 6 pairs in the tank, definitely not overcrowded.

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[yin alessa]

Thank everybody for responding to my post.  My fish are transgenic
lines expressing dsred. I raise them the same way as all the other
fish we have in the fishroom, but only this batch has the problem:
small fish with kinky body. Now I tried to raise the male and females
separately and see what happens.

However, I also generated other transgenic lines with the same
promoter.  I found that those fish are also weaker than any other fish
I have. They seem to age faster.  When I crossed them with other fish,
few of them got killed in the crossing tank. They also seem to need
longer time to recover after crossing.  Has anybody had the
experiences like this?  Any suggestion is highly appreciated!

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[Claudia-3]

On Aug 2, 12:42 pm, yin alessa <yin.ale...@...> wrote:

> Thank everybody for responding to my post.  My fish are transgenic
> lines expressing dsred. I raise them the same way as all the other
> fish we have in the fishroom, but only this batch has the problem:
> small fish with kinky body. Now I tried to raise the male and females
> separately and see what happens.
>
> However, I also generated other transgenic lines with the same
> promoter.  I found that those fish are also weaker than any other fish
> I have. They seem to age faster.  When I crossed them with other fish,
> few of them got killed in the crossing tank. They also seem to need
> longer time to recover after crossing.  Has anybody had the
> experiences like this?  Any suggestion is highly appreciated!

It could be a problem due to inbreeding. We see a similar trend in our
facility where we are trying to inbreed our mutant fish to achieve a
homogeneous gene pool much like they do with mice. The problem we are
seeing is that after 5-6 generations of mating siblings (no group
spawn) the fish have deformations of their jaws and spine and overall
the fish do not grow as well and stay skinny they also eat less.

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